I am having 2 central locations, 1 in the loft and 1 in the cellar to avoid having to create a riser and to reduce cable runs. I will have a gigabit link between the 2 and am installing a 96 port patch panel in each to allow me to route things ad-hoc.
Each light will go back to these 2 points where I will have a distribution board. Relays will perform the switching all located centrally on the 2 distribution boards. This makes maintenance easy and reduces the number of points of failure. In house having a single or couple of points of failure is desirable as it means you don't have to start ripping up walls and floor boards.
Although CAT5 is going in, I may in most cases just use it for the the shielded twisted pairs. As there are 4 pairs you can send data and power down the same cable without creating too much noise. Also if you change your mind you can convert them to standard cat5 cables.
Check out some of my active threads for ideas.
Andy