Can you supply the N+ with 5V through the header at the same time as having the USB connected?
If yes, then will the USB power be disconnected and still allow debugging?
From what I'm seeing, the only thing that plugging in the USB and powering the 5V through the header would do is make the current flow between everything connected. I isolated the flow from the Netduino using a diode connected to the 5V header so that it could flow in, but not out, which I think will keep me safe from drawing an excessive load from the Netduino in the case that something big were plugged into it. When I did have my LEDs connected and not isolated, they worked, they were just really dim. I didn't want to chance it, though, so I isolated it. The way my project works now is that it can be powered by either the USB or the external power supply, or both, and in the case of only the USB, the LEDs receive no power. With the combination of a cable that lets me supply current through an ethernet cable, I now have a single cable connecting to the project with a USB port exposed that I can use for updates. I'm going to be running with this configuration for a few days and see how it goes in the wild. If it blows up, I'll post back here.